Pipeline

An expanding portfolio

Aquestive Therapeutics is the undisputed leader in developing and delivering medications via film, through PharmFilm® technology. Building on this success, we have established a robust portfolio of transformative, simplified products to improve patients’ lives.

Reinventing medicines

Our investigational medicines can offer simple new ways for patients and caregivers to use proven and trusted molecules. Our pipeline includes several investigational treatments for patients facing challenges in using their prescribed medication. Looking ahead, we see even greater potential for PharmFilm® technology to improve patient treatment and are working to deliver simplified, complex molecules, proteins, and peptides on oral film with newer prodrugs and technologies.

Product Pipeline

Click for details
Program
Molecule
Targeted Indication
Formulation    Pre-Clinical/Proof of Concept    Phase 1    Phase 2    Phase 3    Filed    Marketed
CNS Programs
LIBERVANTTM*
(EX US Partner: Pharmanovia)
diazepam
Breakthrough Seizures / Cluster Seizures

Tentative Approval Granted

Tentative approval granted; expected launch in 2027

In development as an oral rescue therapy for breakthrough seizures / cluster seizures

Complex Molecule Programs
ANAPHYLM™*
epinephrine
Anaphylaxis

Clinical

Received conditional proprietary approval from FDA

Emergency treatment of allergic reactions including anaphylaxis

AQST-108
epinephrine
(Alternative Indications)

Clinical

Clinical

In development as a treatment for anaphylaxis, severe allergy

Licensed programs
SUBOXONE®
(Partner: Indivior)
buprenorphine / naloxone

FDA Approved 2010

FDA Approved 2010

ZUPLENZ®
(Ondif in Brazil)
ondansetron

FDA Approved 2010

FDA Approved 2010

SYMPAZAN®
(Partner: Otter Pharmaceuticals)
clobazam

FDA Approved 2018

FDA Approved 2018

EXSERVANTM
(EU Partner: Zambon;
US Partner: Mitsubishi Tanabe;
Chinese Partner: Haisco)
riluzole

FDA Approved 2019

FDA Approved 2019

KYNMOBITM
(Partner: Sunovion)
apomorphine

FDA Approved 2020

FDA Approved 2020

AZSTARYS®
(Partner: Corium)
serdexmethylphenidate and dexmethylphenidate

FDA Approved 2021

FDA Approved 2021

Essential information for the investment community

Aquestive sponsored clinical trials

Clinical trial news and other updates

Please complete this form:

  • To subscribe to receive information updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing info@aquestive.com or by calling 1-908-941-1900.
  • This field is for validation purposes and should be left unchanged.

Please complete the form below and click SEND to receive a copy of “Overcoming Solubility and Permeability Challenges,” a case study detailing the achievements made by Aquestive’s formulation team to create the diazepam buccal film.

  • To subscribe to receive marketing updates about diazepam buccal film and other products and services from Aquestive, please complete the form below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete the form to receive a demonstration kit for our PharmFilm® technology.

  • To subscribe to receive marketing updates about our PharmFilm® technology and other products and services from Aquestive, please complete the form below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete this form:

  • To subscribe to receive marketing updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. If for any reason you no longer wish to receive information on Aquestive-sponsored clinical trials, you can contact us at any time by emailing clinicaltrials@aquestive.com.

Whether we are partnering to out license our PharmFilm® technology or in-licensing adjacent assets, Aquestive works hand-in-hand with our partners to address their toughest clinical and business challenges. To learn more, please complete the following form:

  • To subscribe to receive information updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete the form below and click submit to receive a copy of “The Art of LGS Book.”

Please complete our short form to speak with a business development specialist.