Pipeline

An expanding portfolio

Aquestive Therapeutics is the undisputed leader in developing and delivering medications via film, through PharmFilm® technology. Building on this success, we have established a robust portfolio of transformative, simplified products to improve patients’ lives.

Reinventing medicines

Our investigational medicines can offer simple new ways for patients and caregivers to use proven and trusted molecules. Our pipeline includes several investigational treatments for patients facing challenges in using their prescribed medication. Looking ahead, we see even greater potential for PharmFilm® technology to improve patient treatment and are working to deliver simplified, complex molecules, proteins, and peptides on oral film with newer prodrugs and technologies.

Product Pipeline

Click for details
Program
Molecule
Targeted Indication
Formulation    Pre-Clinical/Proof of Concept    Phase 1    Phase 2    Phase 3    Filed    Marketed
CNS Programs
LIBERVANTTM*
(Seeking Partner Outside US)
diazepam
Breakthrough Seizures / Cluster Seizures

Tentative Approval Granted

Tentative approval granted; expected launch in 2027

In development as an oral rescue therapy for breakthrough seizures / cluster seizures

Complex Molecule Programs
AQST-108
epinephrine
(Alternative Indications)

Clinical

Clinical

In development as a treatment for anaphylaxis, severe allergy

AQST-109
epinephrine
Anaphylaxis

Clinical

Clinical

In development as a pro drug treatment for anaphylaxis, severe allergy

Licensed programs
SUBOXONE®
(Partner: Indivior)
buprenorphine / naloxone

Marketed since 2010

Marketed since 2010

ZUPLENZ®
(Partner: Hypera Brazil)
ondansetron

Marketed since 2010

Marketed since 2010

KYNMOBITM
(Partner: Sunovion)
apomorphine

Approved since 2020

Approved since 2020

EXSERVANTM
(EU Partner: Zambon;
US Partner: Mitsubishi Tanabe)
riluzole

Licensed since 2019

Licensed since 2019

Azstarys®
(Partner: Corium)
serdexmethylphenidate and dexmethylphenidate

Approved since 2021

Approved since 2021

*Aquestive has received conditional acceptance of the use of this trade name, which is subject to final FDA review and acceptance

Subject to review, evaluation, and approval of the FDA

 

Essential information for the investment community

Aquestive sponsored clinical trials

Clinical trial news and other updates

Please complete this form:

  • To subscribe to receive information updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing info@aquestive.com or by calling 1-908-941-1900.

Please complete the form below and click SEND to receive a copy of “Overcoming Solubility and Permeability Challenges,” a case study detailing the achievements made by Aquestive’s formulation team to create the diazepam buccal film.

  • To subscribe to receive marketing updates about diazepam buccal film and other products and services from Aquestive, please complete the form below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete the form to receive a demonstration kit for our PharmFilm® technology.

  • To subscribe to receive marketing updates about our PharmFilm® technology and other products and services from Aquestive, please complete the form below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete this form:

  • To subscribe to receive marketing updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. If for any reason you no longer wish to receive information on Aquestive-sponsored clinical trials, you can contact us at any time by emailing clinicaltrials@aquestive.com.

Whether we are partnering to out license our PharmFilm® technology or in-licensing adjacent assets, Aquestive works hand-in-hand with our partners to address their toughest clinical and business challenges. To learn more, please complete the following form:

  • To subscribe to receive information updates about products and services from Aquestive Therapeutics, or to receive information about Aquestive-sponsored clinical trials, please check the box below. Please also review our privacy policy, which describes how we use and process your data. You may also contact us at any time by emailing busdev@aquestive.com.

Please complete the form below and click submit to receive a copy of “The Art of LGS Book.”